At Zaccha, science meets proof and purpose

Scientific innovation designed to help you live your best years

The science of immune health: your body’s natural defence force

Immune health is the key to healthy aging

A well-functioning immune system plays an important role in overall well-being. Over time, immune function influences how the body maintains strength and resilience. Supporting your immune health today helps you stay strong and resilient for decades to come.

Balance is the key to immune health

Immune health isn’t just about ‘boosting’—it’s about balance. Immune modulation helps your body respond appropriately: activating defenses when needed and calming overactive responses. This balance is key healthy aging.

Role of T cells—”master conductor” in the immunological orchestra

T cells are an important part of the adaptive immune system, helping the body recognise and respond to potential threats. They play important role in immune coordination and immune memory. Maintaining healthy T-cell function supports balanced immune activity and overall well-being.

Bioactive polysaccharides’ benefits on immune health

Bioactive polysaccharides are natural complex carbohydrates known for their powerful benefits on immune health. They balance immune activation and regulation while strengthening the body’s defenses and promote overall well-being. Read more about the science and functions of bioactive polysaccharides.

GPComplex® patented bioactive polysaccharide

GPComplex®, extracted from Chinese licorice root through our patented process, has been extensively studied for its immune health benefits. Chinese licorice root is a superior source of bioactive polysaccharides, valued for its medicinal properties, safety, versatility, and minimal interaction with other supplements or medications.

GPComplex® works in our body through two pathways

About 70% of immune cells reside in the gut, within the gut-associated lymphoid tissue (GALT) defence system. GPComplex® works directly by activating receptors on immune cells in GALT, triggering T-cell activation.

It also works indirectly by acting like a prebiotic, feeding beneficial gut microbiome to strengthen the gut barrier, supporting overall immune balance.

scientist checking t-cell activator in microscope

Not all immune health supplements are made equal

While others only rely on stories, we rely on clinical evidence — because your health deserves proof, not just promises

The bioactivities of GPComplex® are clinically tested to the highest standard

While 99% of health supplements are sold without rigorous human testing—since they are generally regarded as safe and often regulated as food—we went above and beyond, investing in 5 rigorous human trials to ensure both real-world efficacy and safety, making GPComplex® one of the top evidence-based ingredients for immune health.

SEE OUR CLINICAL STUDIES

Published studies on licorice bioactive polysaccharide

Published in: BMC Complementary and Alternative Medicine (2016)

Published in: Nutrients (2025)

Published in: Frontiers in Pharmacology (2024)

Published in: Frontiers in Immunology (2022)

Published in: International Journal of Biological Macromolecules (2021)

Published in: PeerJ (2020)

Published in: Biomolecules (2020)

Published in: International Immunopharmacology (2008)

Our scientific advisory board

Dr. JEREMY LIM

Dr. Jeremy Lim leads AMILI, Southeast Asia’s first dedicated gut microbiome company. He is trained in surgery and preventive medicine and serves as adjunct faculty at the National University of Singapore. He also regularly consults for global organisations such as the World Health Organization and World Bank.

PROF. BIAN YU HONG

Prof. Bian is the Dean of the School of Integrated Chinese and Western Medicine at Tianjin University of Traditional Chinese Medicine, China. A renowned expert in integrating Chinese and Western medicine, she was trained in immunology and cell biology in the UK. She holds a UK patent and has published over 100 papers, including more than 30 indexed by SCI.

Dr. WEILI XU

Dr. Xu obtained his Ph.D. in Immunology (A*STAR-SIgN × Nanyang Technological University) in Singapore, with a thesis on T cells and immune aging. He has contributed to research in areas including cancer, COVID-19, inflammatory bowel disease, and dengue, and has over 20 publications, with an h-index of 15 and more than 1,500 citations.